Author

Michael F. Herfs

University of LiègeORCID 0000-0002-4382-8997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Fabienne PeriniD· 2 shared Alex von KriegsheimiD· 1 shared Anisa AlijuiD· 1 shared Anne PeigneyiD· 1 shared Arnaud BlommeiD· 1 shared Chinmayi PednekariD· 1 shared Christian Seca· 1 shared Christine Schaeffer‐ReissiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Fabienne PerinORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

mTORC2 stabilizes HIF-1β to coordinate metabolic adaptation in lung cancer

Morgane Paque, Ning An, Marine Leclercq, Anisa Aliju, Elodie Renaude, Domien Vanneste, Denis Heusdens, Jair Marques, Chinmayi Pednekar, Tillmann Bedau, Juan Fernández-García, Fabienne Perin, Raphael Vanleyssem, Christian Seca, Kim Eiden, , Arnaud Blomme

This study identifies mTORC2 as a convergent dependency in lung cancer that stabilizes HIF-1β to drive metabolic adaptation and tumor progression, revealing a therapeutic target in sphingolipid metabolism.

bioRxiv · Sep 3, 2026 · PreprintCancer Biology

KDM6B interacts with nucleo-adhesome components CSRP2 and TGFB1I1 to regulate EMT

Jules Durand, Montagnon Frederic, Sarahi Jaramillo-Ortiz, Christine Schaeffer‐Reiss, Michael F. Herfs, Marie‐Julie Nokin, Diane Bruyère, Fabienne Perin, Jean‐René Pallandre, Christophe Borg, Anne Peigney, Overs Alexis, Mathieu Lupien, Michaël Boyer‐Guittaut, Éric Hervouet, , Paul Peixoto

This paper identifies KDM6B interacting with nucleo-adhesome proteins CSRP2 and TGFB1I1 to regulate EMT-related genes in lung cancer cells.

bioRxiv · Aug 25, 2026 · PreprintCell Biology