Author

Jair Marques

Cancer Research UK

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alex von KriegsheimiD· 2 shared Alessandro ScopellitiiD· 1 shared Amanda O. WongiD· 1 shared Anisa AlijuiD· 1 shared Anna E. Davey· 1 shared Arnaud BlommeiD· 1 shared Charlotte DawsoniD· 1 shared Chinmayi PednekariD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Alex von KriegsheimORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

mTORC2 stabilizes HIF-1β to coordinate metabolic adaptation in lung cancer

Morgane Paque, Ning An, Marine Leclercq, Anisa Aliju, Elodie Renaude, Domien Vanneste, Denis Heusdens, Jair Marques, Chinmayi Pednekar, Tillmann Bedau, Juan Fernández-García, Fabienne Perin, Raphael Vanleyssem, Christian Seca, Kim Eiden, , Arnaud Blomme

This study identifies mTORC2 as a convergent dependency in lung cancer that stabilizes HIF-1β to drive metabolic adaptation and tumor progression, revealing a therapeutic target in sphingolipid metabolism.

bioRxiv · Sep 3, 2026 · PreprintCancer Biology

Intestinal bacteria hijack an evolutionarily conserved epithelial repair signal

Sam Benson, Priscilla Chin, Sebastian Rogatti, Alessandro Scopelliti, Luigi Zechini, Rosalind Heron, Charlotte Dawson, Anna E. Davey, Mariska S. Simpson, Amanda O. Wong, Jair Marques, Alex von Kriegsheim, David Harold Dockrell, Christopher D. Lucas, Jenna L. Cash, , Christopher J. Anderson

The paper identifies hypoxanthine as a key metabolite released during apoptosis that is consumed by gut bacteria, impairing epithelial repair.

bioRxiv · Aug 11, 2026 · PreprintMicrobiology