Weihua Qin

The paper investigates how heterochromatin proteins form barrier compartments in cells, showing differences between proteins, cell types, and compartments, and proposes a model based on protein accumulation and competition.

This study identifies USP7 and ATAD5 as key factors in terminating UHRF1-dependent PAF15 ubiquitin signaling, linking this process to the completion of maintenance DNA methylation.

The paper identifies DPPA3 as a driver of genome-wide passive DNA demethylation in mammals, showing it can bypass TET protein requirements and function across species.