Judith Gallant

The paper describes a method to achieve high-efficiency targeted transgene integration in zygotes, producing non-mosaic transgenic animals without requiring mosaic breeding.

This study shows that 5' modifications to DNA repair templates enhance precision genome editing efficiency in multiple animal models and human cells.

This study analyzes 21 pre-E9.5 lethal mouse lines to identify developmental milestones associated with embryo lethality and provides insights into early mammalian development and human disease mechanisms.