Jaime A. Rivera‐Pérez

The paper describes a method to achieve high-efficiency targeted transgene integration in zygotes, producing non-mosaic transgenic animals without requiring mosaic breeding.

The paper identifies Sfrp2 as a multifunctional regulator controlling coat pattern and color in African striped mice through transcriptomics, modeling, and gene editing.

This study shows that 5' modifications to DNA repair templates enhance precision genome editing efficiency in multiple animal models and human cells.

This study analyzes 21 pre-E9.5 lethal mouse lines to identify developmental milestones associated with embryo lethality and provides insights into early mammalian development and human disease mechanisms.

This study shows that small RNAs acquired by sperm in the epididymis are critical for embryonic development in mice, as their absence leads to developmental failure and can be rescued by adding these RNAs.