Kevin R. Amses

The paper analyzes immune cell changes in human pancreas-draining lymphatic tissues before and after T1D onset, identifying proinflammatory patterns and genetic risk correlations.

The paper shows that in 3D forebrain organoids, neurons and neural progenitors use type I interferon signaling to limit viral spread through intercellular communication.

This study shows that type I interferon reduces extravillous trophoblast invasion and induces a preeclampsia-like gene signature in an organ-on-a-chip model of implantation.

This study shows that targeting TET2 in CAR T-cells improves their anti-tumor responses by limiting terminal exhaustion and enhancing therapeutic potential.

The paper identifies human erythroid progenitors as immune mediators expressing MHC class II machinery and interacting with T cells in the fetal liver.