Cell BiologybioRxiv
HNF4α-TET2-FBP1 axis contributes to gluconeogenesis and type 2 diabetes
Hongchen Li, Xinchao Zhang, Xiaoben Liang…·Yanping Xu
This study identifies an HNF4-TET2-FBP1 axis that regulates gluconeogenesis and shows metformin's effect on this pathway in type 2 diabetes.
2 citations