Moritz Weigl

miRISC inhibition causes mitotic defects and synergizes with genotoxic agents in cancers

The paper shows that inhibiting the HMWR complex causes mitotic defects and enhances cancer cell vulnerability when combined with genotoxic agents.

Profiling microRNA expression during senescence and aging: mining for a diagnostic tool of senescent-cell burden

The paper profiles miRNA expression during senescence and aging to identify potential circulating biomarkers of senescent cell burden in mice and humans.

SVF-derived extracellular vesicles carry characteristic miRNAs in lipedema

This study compares extracellular miRNA profiles in lipedema and healthy adipose tissue, finding that sEV miRNAs are differentially regulated in lipedema.

MiR-146a controls age related bone loss

This study identifies miR-146a as a key regulator of age-related bone loss, showing its role in controlling bone homeostasis through Wnt signaling and its potential as a therapeutic target.

MicroRNA levels in bone and blood change during bisphosphonate and teriparatide therapy in an animal model of postmenopausal osteoporosis

This study examines miRNA changes in bone and blood during bisphosphonate and teriparatide treatment in an osteoporosis animal model, finding significant miRNA regulation linked to bone remodeling.