Author

Hongchen Li

Hebei Medical UniversityORCID 0000-0003-2639-8726Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:statistical model· 1

Frequent Co-Authors

Bingbing ZhaiD· 1 shared Ebenezer N. YamoahiD· 1 shared Fan ZhangiD· 1 shared Fei WangiD· 1 shared Haichao Yang· 1 shared Haijie MaiD· 1 shared Haitao SheniD· 1 shared Haiwei ZhangiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Bingbing ZhaORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivSep 29, 2024

HNF4α-TET2-FBP1 axis contributes to gluconeogenesis and type 2 diabetes

Hongchen Li, Xinchao Zhang, Xiaoben Liang…·Yanping Xu

This study identifies an HNF4-TET2-FBP1 axis that regulates gluconeogenesis and shows metformin's effect on this pathway in type 2 diabetes.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedSep 20, 2022

Repressor element 1-silencing transcription factor deficiency yields profound hearing loss through Kv7.4 channel upsurge in auditory neurons and hair cells

Haiwei Zhang, Hongchen Li, Mingshun Lu…·Ping Lv

This study shows that REST deficiency leads to increased Kv7.4 channels in auditory neurons and hair cells, causing progressive hearing loss, which can be reversed by Kv7.4 inhibition.

5 citations

mouseelectronic health records

𝕏 PostBluesky