Author

Gwladys Rivière

German Center for Neurodegenerative DiseasesORCID 0000-0002-4488-2813Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Research Focus:cell type annotation· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

Markus ZweckstetteriD· 2 shared Alain Ibáñez de OpakuaiD· 1 shared Aleksandra M. KusovaiD· 1 shared Anne‐Laure Mahul‐MellieriD· 1 shared Ansel HsiaoiD· 1 shared Frank SobottiD· 1 shared Hilal Ahmed LashueliD· 1 shared Iman RostamiiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersBiophysics

Markus ZweckstetterORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 20, 2026

A Heart Disease-Associated TSPO Variant Alters Transmembrane Helix Dynamics

Aleksandra M. Kusova, Gwladys Rivière, Karin Giller…·Markus Zweckstetter

The paper investigates how a disease-associated TSPO variant affects transmembrane helix dynamics using solution NMR spectroscopy.

DOI 10.64898/2026.04.10.717289

humanprotein structure

𝕏 PostBluesky

BiophysicsbioRxivPreprintFeb 27, 2026

Allosteric Inhibition of NDM-1 by Thanatin Preserves the Di-Zinc Center While Restricting Dynamics

Gwladys Rivière, Prince Kumar, Tom Cummins…·Leonard J. Mueller

This paper reveals that Thanatin inhibits NDM-1 by preserving its zinc center while restricting dynamics, contrasting with zinc-displacement models and showing reduced bacterial viability.

DOI 10.64898/2026.02.25.707299

protein structuremechanistic / dynamical model

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 21, 2021

A novel mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein fibrils and recapitulates its pathological diversity

Senthil T. Kumar, Anne‐Laure Mahul‐Mellier, Ramanath Narayana Hegde…·Hilal Ahmed Lashuel

The paper investigates the effects of the E83Q mutation on alpha-synuclein aggregation and toxicity, finding it accelerates fibrillization and enhances pathological features in neuronal models.

3 citations

humanproteomics

𝕏 PostBluesky