Ryan E. Tyler

This study evaluates the effects of SBI-553, a β-arrestin-biased allosteric modulator of NTSR1, on ethanol-related behaviors in rodents, finding reduced ethanol consumption and altered sensitivity to ethanol effects.

This study shows that predator odor stress increases male rats' sensitivity to alcohol via GABAA receptor changes in the prelimbic cortex, but not in females.

This study shows that predator odor exposure increases sensitivity to alcohol's interoceptive effects and boosts GABAergic gene expression in brain regions linked to stress and addiction.

This study investigates how mGlu2 and mGlu3 NAMs affect alcohol's interoceptive effects in rats, finding they reduce these effects in both sexes with potential sex differences in response.

This study investigates how mGlu3 NAM pretreatment affects behavioral and molecular changes in the insular cortex and BNST after predator odor exposure in rats.

This study examines gene expression changes in male rats after TMT exposure, showing early and late molecular adaptations related to stress and excitatory synaptic function.