LUCas: Light-Uncaged Cas13a using photocleavable interfering guide RNAs
Carlos F. Ng, Deepak Krishnamurthy, Andres Dextre…·Daniel A. Fletcher
This paper introduces LUCas, a light-controlled Cas13a system that suppresses background activity and enables precise control of RNA detection, improving assay sensitivity and enabling multiplexed viral co-infection detection.