Ting-Jui Ben Chang

Adaptable centriole biogenesis via the intrinsically disordered protein ALMS1

This study identifies ALMS1 as an intrinsically disordered protein that mediates cartwheel dynamics during centriole biogenesis, showing its role in forming and disassembling cartwheel seeds and enabling adaptable centriole formation.

SSNA1 organizes the distal luminal centriolar network and promotes ciliogenesis without microtubule association

This study identifies SSNA1 as a centriolar protein in the distal lumen that promotes ciliogenesis without microtubule association, challenging previous views of its function.