Author

Jens Lüders

Institute for Research in BiomedicineORCID 0000-0002-9018-7977Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alexandra JunzaiD· 1 shared Antonio HerreraiD· 1 shared Avital Shulman· 1 shared Cedric A. BoeckxiD· 1 shared Denisse Izquierdo· 1 shared Ilaria Dutto· 1 shared Jordann A Smak· 1 shared Julian GerhardsiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperDevelopmental Biology

Alexandra JunzaORCID

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Author profile →

2 papers

Recent·Most cited

Adaptable centriole biogenesis via the intrinsically disordered protein ALMS1

Kanako Ozaki, Ting-Jui Ben Chang, Wen-Qing Yang, Avital Shulman, Denisse Izquierdo, Wann‐Neng Jane, Won‐Jing Wang, Tim Stearns, Jens Lüders, T. Tony Yang, Meng-Fu Bryan Tsou

This study identifies ALMS1 as an intrinsically disordered protein that mediates cartwheel dynamics during centriole biogenesis, showing its role in forming and disassembling cartwheel seeds and enabling adaptable centriole formation.

Nature Communications · Jun 30, 2026Peer-reviewedCell Biology

SAICAr-dependent and independent effects of ADSL deficiency on neurodevelopment

Ilaria Dutto, Julian Gerhards, Antonio Herrera, Olga Souckova, Václava Škopová, Jordann A Smak, Alexandra Junza, Óscar Yanes, Cedric A. Boeckx, Martin D. Burkhalter, Marie Zikánová, Sebastián Pons, Melanie Philipp, Jens Lüders, Travis H. Stracker

This study investigates the effects of ADSL deficiency on neurodevelopment, showing both SAICAr-dependent and independent mechanisms contributing to pathologies like microcephaly and autism.

eLife · Feb 8, 2022Peer-reviewedDevelopmental Biology