Author

Panwen Wang

Mayo Clinic in ArizonaORCID 0000-0002-4614-8970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:benchmarking· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Junwen WangiD· 3 shared Li LiuiD· 3 shared Ping YangiD· 3 shared Zhifu SuniD· 3 shared Changxin Shi· 2 shared Hai CheniD· 2 shared Jingmin Shu· 2 shared Peter Leif BergsageliD· 2 shared

Activity by Year

2022-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBioinformatics

Junwen WangORCID

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Author profile →

5 papers

Recent·Most cited

Germline regulation of tumor evolutionary dynamics shapes multiple myeloma progression

Hai Chen, Jingmin Shu, Rekha Mudappathi, Panwen Wang, Peter Leif Bergsagel, Ping Yang, Zhifu Sun, Changxin Shi, Li Liu

This study links germline variation to tumor evolutionary dynamics in multiple myeloma, identifying TBKBP1 as a mediator of subclonal expansion and clinical outcomes.

bioRxiv · Jun 7, 2026 · PreprintBioinformatics

ceQTL: A co-expression QTL model to detect a variant that affects transcription factor binding and its target regulation

Panwen Wang, Yanxi Chen, Yong Liu, Li Liu, Ping Yang, Junwen Wang, Zhifu Sun

The paper introduces ceQTL, a method to detect eQTLs that affect transcription factor binding and target gene regulation using differential co-expression analysis.

Briefings in Bioinformatics · May 1, 2026Peer-reviewedBioinformatics

Competing Subclones and Fitness Diversity Shape Tumor Evolution Across Cancer Types

Hai Chen, Jingmin Shu, Rekha Mudappathi, Elaine Li, Panwen Wang, Peter Leif Bergsagel, Ping Yang, Z Sun, Logan Zhao, Changxin Shi, Jeffrey P Townsend, Carlo C. Maley, Li Liu

TEATIME estimates evolutionary parameters and fitness diversity from bulk sequencing data, revealing patterns of intratumor heterogeneity across 33 cancer types.

Bioinformatics · Feb 28, 2026Peer-reviewedBioinformatics

Immunopipe: A comprehensive and flexible scRNA-seq and scTCR-seq data analysis pipeline

Panwen Wang, Yue Yu, Haidong Dong, Shuwen Zhang, Zhifu Sun, Hu Zeng, Patrizia Mondello, Jean‐Pierre Kocher, Junwen Wang, Yan W. Asmann, Yi Lin, Ying Li

Immunopipe provides a flexible pipeline for integrated analysis of scRNA-seq and scTCR-seq data to enhance understanding of T-cell immunity and immunotherapy.

NAR Genomics and Bioinformatics · Mar 29, 2025Peer-reviewedBioinformatics

Integrating Transcriptomics, Genomics, and Imaging in Alzheimer's Disease: A Federated Model

Jianfeng Wu, Yanxi Chen, Panwen Wang, Richard J. Caselli, Paul M. Thompson, Junwen Wang, Yalin Wang, Alzheimer’s Disease Neuroimaging Initiative

This paper introduces a federated model to integrate sMRI, GWAS, and transcriptomics data in Alzheimer's disease to identify genetic and transcriptomic influences on brain imaging measures.

Frontiers in Radiology · Jan 21, 2022Peer-reviewedBioinformatics