Kai Guo

This study shows that reduced mitochondrial fitness in CD8 T cells, caused by TFAM insufficiency, leads to increased immunopathology during viral pneumonia and impaired protective immunity.

The paper benchmarks differential rhythmicity analysis methods and introduces a web platform for robust analysis and visualization of rhythmicity changes.

This study shows that influenza co-infection disrupts epithelial tolerance to Streptococcus pneumoniae via NF-κB driven inflammation, leading to bacterial invasion and highlighting TRAF6-NF-κB as a therapeutic target.

The paper modifies Escherichia coli MG1655 to create a more efficient host strain for chemical production by inactivating DNA defense systems, resulting in higher transformation efficiency and plasmid stability.