Author

Thenzing J. Silva-Hurtado

InsermORCID 0000-0002-4697-6055Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Olivier LassalleiD· 2 shared Pascale ChavisiD· 2 shared Antoine AmelootiD· 1 shared Balagopal PaiiD· 1 shared Elena ZaslavskyiD· 1 shared Emine ÖzeniD· 1 shared Gabriele GiuaiD· 1 shared Gabrielle A. PriceiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Olivier LassalleORCID

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3 papers

Recent·Most cited

Spatial multi-omics defines a shared infiltrative signature in glioblastoma at the resection margin

Balagopal Pai, Susana Isabel Ramos, Wan Sze Cheng, Tanvi Joshi, Emine Özen, Lakshmi Shree Kulumani Mahadevan, Thenzing J. Silva-Hurtado, Gabrielle A. Price, Jessica Tomé-García, German Nudelman, Sanjana Shroff, Kristin G. Beaumont, Raymund L.M. Yong, Robert Sebra, Elena Zaslavsky, Nadejda M. Tsankova

This study identifies a shared infiltrative signature in glioblastoma at the resection margin using spatial multi-omics data and validates EGFR as a key marker.

Cancer Research · Aug 4, 2025Peer-reviewedCancer Biology

SEX-SPECIFIC TRAJECTORIES OF REELIN-DEPENDENT MATURATION OF DEEP LAYER PREFRONTAL NEURONS

Thenzing J. Silva-Hurtado, Olivier Lassalle, Antoine Ameloot, Pascale Chavis

This study investigates how reelin affects the sex-specific maturation of prefrontal cortex neurons and synaptic plasticity in mice.

bioRxiv · Dec 23, 2021 · PreprintNeuroscience

Cannabinoid during adolescence phenocopies reelin haploinsufficiency in prefrontal cortex synapses

Thenzing J. Silva-Hurtado, Gabriele Giua, Olivier Lassalle, Michelle N. Murphy, Jim Wager‐Miller, Ken Mackie, Olivier J. Manzoni, Pascale Chavis

This study shows that adolescent cannabinoid exposure reduces prefrontal reelin expression and impairs synaptic plasticity, mimicking reelin haploinsufficiency.

bioRxiv · Dec 22, 2021 · PreprintNeuroscience