Fei Gao

TRUEDA identifies true pathogens in low-biomass disease-microbe associations by accounting for contamination, outperforming existing decontamination methods and correcting false associations.

This paper develops a synergistic RNA switch system that enhances gene expression control by integrating multiple regulatory modules, achieving improved inducibility and reduced off-target effects.

This study shows that single-AAV delivery of base editors can achieve effective cardiac gene silencing with higher success rates than dual-AAV systems.