Monica H. Dawes

This study shows that KOR activation leads to DAT tolerance to cocaine via phosphorylation at threonine 53, demonstrated through behavioral, electrophysiological, and genetic experiments across species.

This study shows that synaptogyrin-3 reduces cocaine self-administration and prevents dopamine deficits by enhancing dopamine signaling and cognitive flexibility in rats.

This study examines how adding nicotine to cocaine self-administration in rats affects behavior under different reinforcement schedules, finding reduced responding under long access but increased responding under progressive ratio conditions.

This study shows that chronic heroin self-administration reduces basal dopamine levels and alters dopamine release dynamics in the nucleus accumbens, potentially contributing to increased heroin seeking.