Alyson M. Curry

This study shows that KOR activation leads to DAT tolerance to cocaine via phosphorylation at threonine 53, demonstrated through behavioral, electrophysiological, and genetic experiments across species.

This study identifies NARH as a SIRT5 modulator that differentially regulates its desuccinylation and deacetylation activities, providing insights into SIRT5 regulation and a chemical scaffold for activator development.

This study characterizes PfSir2A's biochemical properties and identifies inhibitors, revealing its nucleosome and fatty acid regulation and discovering small molecule inhibitors for antimalarial development.

This study shows that synaptogyrin-3 reduces cocaine self-administration and prevents dopamine deficits by enhancing dopamine signaling and cognitive flexibility in rats.