Katherine M. Holleran

This study shows that KOR activation leads to DAT tolerance to cocaine via phosphorylation at threonine 53, demonstrated through behavioral, electrophysiological, and genetic experiments across species.

This study shows that KOR activation delays sucrose self-administration by reducing dopamine ramps before lever pressing in mice.

The paper compares three methods for analyzing spontaneous dopamine signals and finds that z-scoring is unreliable, while manual and prominence methods are more accurate.

The paper examines how chronic alcohol drinking affects the relationship between gene expression and dopamine regulation in the brain, finding persistent functional changes despite no change in transcript levels.

This study shows that synaptogyrin-3 reduces cocaine self-administration and prevents dopamine deficits by enhancing dopamine signaling and cognitive flexibility in rats.

This study shows that KOR activation reduces dopamine release and increases uptake, leading to decreased spontaneous dopamine signals in both male and female mice.

This study examines how adding nicotine to cocaine self-administration in rats affects behavior under different reinforcement schedules, finding reduced responding under long access but increased responding under progressive ratio conditions.