Synaptogyrin-3 Prevents Cocaine Addiction and Dopamine Deficits
Emily G. Peck, Katherine M. Holleran, Alyson M. Curry, Kimberly M. Holter, Paige M. Estave, Jonathon P. Sens, Jason L. Locke, Olivia A. Ortelli, Brianna E. George, Monica H. Dawes, Alyssa M. West, Nancy J. Alexander, Drew D. Kiraly, Sean P. Farris, Robert W. Gould, , Sara R. Jones
This study shows that synaptogyrin-3 reduces cocaine self-administration and prevents dopamine deficits by enhancing dopamine signaling and cognitive flexibility in rats.
bioRxiv · Jul 27, 2024 · PreprintNeuroscience