Author

Madeline Nicholson

The University of MelbourneORCID 0000-0002-4740-8658Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Jessica L. FletcheriD· 2 shared Simon S. MurrayiD· 2 shared Alanna Gabrielle SpiteriiD· 1 shared Anjie GeiD· 1 shared Anthony John HannaniD· 1 shared Anthony Simon DoniD· 1 shared David G. GonsalveziD· 1 shared Holly P. McEweniD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Jessica L. FletcherORCID

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2 papers

Recent·Most cited

Early microglial response, myelin deterioration and lethality in mice deficient for very long chain ceramide synthesis in oligodendrocytes

Jonathan D. Teo, Oana C. Marian, Alanna Gabrielle Spiteri, Madeline Nicholson, Huitong Song, Jasmine X. Y. Khor, Holly P. McEwen, Anjie Ge, Monokesh Kumer Sen, Laura M. Piccio, Jessica L. Fletcher, Nicholas J. C. King, Simon S. Murray, Jens C. Brüning, Anthony Simon Don

This study shows that mice lacking CerS2 in oligodendrocytes develop myelin instability, microglial activation, and early lethality due to reduced C22-C24 sphingolipids.

Glia · Dec 30, 2022Peer-reviewedNeuroscience

Remodeling of pre-existing myelinated axons and oligodendrocytes is stimulated by environmental enrichment in the young adult brain

Madeline Nicholson, Rhiannon J. Wood, Jessica L. Fletcher, David G. Gonsalvez, Anthony John Hannan, Simon S. Murray, Junhua Xiao

This study shows environmental enrichment stimulates structural remodeling of pre-existing myelinated axons and oligodendrocytes in young adult mice, increasing axon diameter and myelin thickness without enhancing new myelin production.

bioRxiv · Jan 21, 2020 · PreprintNeuroscience