Author

Tyler L. Grove

Albert Einstein College of MedicineORCID 0000-0002-4763-0646Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

Aaron R. GoldmaniD· 1 shared Adam M. GlassiD· 1 shared Andrew V. KossenkoviD· 1 shared Bhanu Chandra KarisettyiD· 1 shared Chengyu LiangiD· 1 shared Erica L. SchwalmiD· 1 shared Hyunwook LeeiD· 1 shared James JungiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Aaron R. GoldmanORCID

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2 papers

Recent·Most cited

Structural Basis for C8 methylation of 23S ribosomal RNA by Cfr

Olga A. Esakova, James Jung, Hyunwook Lee, Sung Hyun Cho, John N. Alumasa, Erica L. Schwalm, Tyler L. Grove, Matthew Bauerle, Susan L. Hafenstein, Zhiheng Yu, Squire J. Booker

The paper determines the Cryo-EM structure of Cfr, revealing its mechanism of C8 methylation on 23S rRNA and its role in antibiotic resistance.

bioRxiv · Mar 2, 2026 · PreprintBiochemistry

RSAD2/VIPERIN and CMPK2 Coordinate an Immunometabolic Response to Epstein-Barr Virus

Urvi S. Zankharia, Adam M. Glass, Wujuan Zhang, Qing Zhu, Janvhi Suresh Machhar, Ying Ye, Bhanu Chandra Karisetty, Jayamanna M. Wickramasinghe, Andrew V. Kossenkov, Jozef Madžo, Sun Sook Chung, Samantha S. Soldan, Richard Jason Lamontagne, James M. Wood, Lawrence D. Harris, , Paul M. Lieberman

This study identifies RSAD2 and CMPK2 as key regulators of EBV reactivation and host interferon responses, revealing their coordinated immunometabolic role in viral latency and immune control.

bioRxiv · Feb 4, 2026Microbiology