Author

Mauricio Aguilar Rangel

Stanford UniversityORCID 0000-0002-4768-9031Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Alice Bedwell· 1 shared Casey Powers· 1 shared Elisa CostanziiD· 1 shared Gonçalo J. L. BernardesiD· 1 shared Haley E. TarboxiD· 1 shared Jaeyoon LeeiD· 1 shared Joseph Daniel PuglisiiD· 1 shared Judith FrydmaniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Alice Bedwell

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2 papers

Recent·Most cited

Translation fidelity mechanisms and their changes in aging

Mauricio Aguilar Rangel, Casey Powers, Jaeyoon Lee, Haley E. Tarbox, Neil B. Wood, Stephen D. Fried, Stephen R. Quake, Joseph Daniel Puglisi

This study measures proteome-wide translation errors in yeast and mouse, finding that fidelity varies by organism and tissue, increases with age in post-mitotic cells, and is regulated by tRNA pool remodeling.

bioRxiv · Sep 25, 2026 · PreprintMolecular Biology

Fragment-based computational design of antibodies targeting structured epitopes

Mauricio Aguilar Rangel, Alice Bedwell, Elisa Costanzi, Ross J Taylor, Rosaria Russo, Gonçalo J. L. Bernardes, Stéfano Ricagno, Judith Frydman, Michele Vendruscolo, Pietro Sormanni

A fragment-based computational method designs nanobodies targeting specific epitopes with nanomolar affinities, without requiring high-resolution antigen structures.

Science Advances · Nov 11, 2022Peer-reviewedBioinformatics