Author

Aidan Pillard

Icahn School of Medicine at Mount SinaiORCID 0000-0002-4780-0887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adolfo Garcı́a-OcañaiD· 2 shared Donald K. ScottiD· 2 shared Esra KaraköseiD· 2 shared Kunal KumariD· 2 shared Luca LambertiniiD· 2 shared Olivia Wood· 2 shared Peng WangiD· 2 shared Robert J. DeVitaiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Adolfo Garcı́a-OcañaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Harmine Selectively Drives Human Beta Cell Differentiation and Function Via Protein Kinase A Pathways

Peng Wang, Kunal Kumar, Luca Lambertini, Hongtao Liu, Olivia Wood, Shuxuan Chen, Aidan Pillard, Donald K. Scott, João A. Paulo, Steven P. Gygi, Susmita Khamrui, Stefan Mueller, Adolfo Garcı́a-Ocaña, Esra Karaköse, Michael B. Lazarus, , Andrew F. Stewart

This paper shows harmine, a DYRK1A inhibitor, selectively promotes human beta cell differentiation and function via PKA activation, distinct from other DYRK1A inhibitors.

bioRxiv · Dec 8, 2025 · PreprintCell Biology

Select DYRK1A Inhibitors Enhance Both Proliferation and Differentiation in Human Pancreatic Beta Cells

Peng Wang, Olivia Wood, Lauryn Choleva, Hongtao Liu, Esra Karaköse, Luca Lambertini, Aidan Pillard, Vickie Wu, Adolfo Garcı́a-Ocaña, Donald K. Scott, Kunal Kumar, Robert J. DeVita, Andrew Francis Stewart

This study identifies harmine, 2-2c, and 5-IT as DYRK1A inhibitors that enhance both beta cell proliferation and differentiation, while others fail to induce differentiation.

bioRxiv · May 17, 2024 · PreprintMolecular Biology