Author

R. Charles Coombes

Imperial College LondonORCID 0000-0002-4811-1100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Ana FariasiD· 1 shared Anisha Ramessur· 1 shared C. ToumazouiD· 1 shared Constandina PosporiiD· 1 shared Felipe Silva RodriguesiD· 1 shared George Alexandrou· 1 shared Ilaria MalanchiiD· 1 shared Izadora Liranço FurlaniiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ana FariasORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 20, 2025

Cancer-driven neutrophil priming couples systemic epithelial regenerative programs with pre-metastatic niche formation

Nicolas Rabas, Victoria Louise Bridgeman, Anisha Ramessur…·Ilaria Malanchi

This study identifies neutrophil-driven systemic conditioning that links inflammation, tissue regeneration, and metastasis, with UPP1 as a key factor in neutrophil priming.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 19, 2022

A comparison between Mini-loop mediated isothermal amplification and polymerase spiral reaction for selective amplification of short template DNA

Rebecca C. Allsopp, George Alexandrou, C. Toumazou…·Jacqui Shaw

This study compares AS-Mini-LAMP and PSR for amplifying short DNA templates, finding AS-Mini-LAMP more effective for mutant allele detection.

DOI 10.1101/2022.05.19.492708

DNA methylationexperimental assay

𝕏 PostBluesky