Victoria Louise Bridgeman

Sex-Dimorphic Neural Memory Shapes Pancreatic Tissue Resilience

The paper identifies a sex-specific neural memory mechanism in the pancreas that influences epithelial plasticity and tissue resilience after injury.

Type I interferons induced upon respiratory viral infection impair lung metastatic initiation

This study shows that type I interferons from respiratory viral infections reduce lung metastasis by altering the lung environment and impairing tumor cell growth.

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

This study shows that integrin conformation-dependent neutrophil slowing in pre-metastatic lungs obstructs capillaries and may contribute to immunosuppression in breast cancer.

Inhibition of neutrophil degranulation by Nexinhib20 delays the development of radiation-induced pulmonary fibrosis

The paper shows that inhibiting neutrophil degranulation with Nexinhib20 delays radiation-induced pulmonary fibrosis without affecting cancer radiotherapy efficacy.

Cancer-driven neutrophil priming couples systemic epithelial regenerative programs with pre-metastatic niche formation

This study identifies neutrophil-driven systemic conditioning that links inflammation, tissue regeneration, and metastasis, with UPP1 as a key factor in neutrophil priming.

Cell-specific Bioorthogonal Tagging of Glycoproteins

The paper introduces BOCTAG, a method to label glycoproteins in specific cell types within mixed cultures, enabling analysis of cell-specific glycosylation.