Dibutyryl cyclic AMP downregulates tenascin-C in neurons and astrocytes and reduces AAV-mediated gene expression in DRG neurons
Kateřina Štěpánková, Anda Cimpean, Barbora Šmejkalová, Radovan Holota, Lenka Bachanova, Jiri Cerny, Vojtech Sprincl, Dana Mareková, Joëlle van den Herik, Fred de Winter, Pavla Jendelová, Lucia Machová Urdzíková
This study investigates the combined effects of db-cAMP and integrin 9 overexpression on axonal regeneration in spinal cord injury models, finding mixed in vitro and in vivo results.
bioRxiv · May 13, 2025 · PreprintNeuroscience