Author

Anda Cimpean

Czech Academy of SciencesORCID 0009-0002-3550-2441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Pavla JendelováiD· 4 shared James W. FawcettiD· 3 shared Dana Mareková· 2 shared Jessica C. F. KwokiD· 2 shared Lucia Machová UrdzíkováiD· 2 shared Barbora ŠmejkalováiD· 1 shared Clifford J. WoolfiD· 1 shared Daniel H. GeschwindiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersNeuroscience

Pavla JendelováORCID

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4 papers

Recent·Most cited

4-Methylumbelliferone Restores Age-Related Changes in Perineuronal Nets, Memory and Neuroinflammation

Anda Cimpean, Jana Dubišová, Noelia Martínez-Varea, Dana Mareková, Lucia Machová Urdzíková, James W. Fawcett, Pavla Jendelová, Jessica C. F. Kwok

This study shows that 4-MU reduces PNNs, improves memory, and decreases neuroinflammation in aged mice.

Glia · Sep 30, 2026Peer-reviewedNeuroscience

Intertwined Autophagy and Integrin Dynamics Shape Axon Growth and Regeneration

Anda Cimpean, Jessica C. F. Kwok, James W. Fawcett, Pavla Jendelová

This study investigates the relationship between autophagy and integrin dynamics in axon growth and regeneration, finding a bidirectional feedback system that regulates these processes.

bioRxiv · Aug 6, 2026 · PreprintNeuroscience

Dibutyryl cyclic AMP downregulates tenascin-C in neurons and astrocytes and reduces AAV-mediated gene expression in DRG neurons

Kateřina Štěpánková, Anda Cimpean, Barbora Šmejkalová, Radovan Holota, Lenka Bachanova, Jiri Cerny, Vojtech Sprincl, Dana Mareková, Joëlle van den Herik, Fred de Winter, Pavla Jendelová, Lucia Machová Urdzíková

This study investigates the combined effects of db-cAMP and integrin 9 overexpression on axonal regeneration in spinal cord injury models, finding mixed in vitro and in vivo results.

bioRxiv · May 13, 2025 · PreprintNeuroscience

Integrin-driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program

Menghon Cheah, Yuyan Cheng, Veselina Petrova, Anda Cimpean, Pavla Jendelová, Vivek Swarup, Clifford J. Woolf, Daniel H. Geschwind, James W. Fawcett

This study identifies a distinct CNS regeneration program activated by integrin expression in spinal cord sensory neurons, differing from PNS regeneration and involving ubiquitination, autophagy, and signaling pathways.

Journal of Neuroscience · Jun 5, 2023Peer-reviewedNeuroscience