Silvia Di Francescantonio

This study identifies the actomyosin cortex, regulated by Arpc5, as critical for t-tubule remodeling in muscle, linking it to muscle function and disorders.

This study shows that myofibers use Arp2/3-dependent membrane protrusions to drive myoblast fusion and myonuclear accretion during postnatal muscle growth.

This study uses CRISPR to correct a dysferlin mutation in muscle stem cells, rescuing protein function and improving muscle regeneration in a mouse model.