Michael Berney

A new Persister Enrichment Model in Mycobacterium tuberculosis links multidrug persistence to drug sequencing and maltokinase-dependent carbon distribution.

This paper introduces a Persister Enrichment Model (PEM) to study multidrug persistence in M. tuberculosis, showing that drug sequencing and maltokinase-dependent carbon distribution influence antibiotic tolerance.

The mycobacterial ATP burst is a lysis artifact and serves as an assay for drug-induced cell wall damage

This study shows the mycobacterial ATP burst is an experimental artifact caused by cell lysis, not a biological response, and presents it as a tool for screening cell wall-disrupting drugs.

Higher-order organization of bacterial cords and an amyloid-like matrix define the Mycobacterium tuberculosis biofilm

This study reveals the structural organization of Mycobacterium tuberculosis biofilms, showing how bacterial cords and an amyloid-like matrix contribute to antibiotic tolerance.

A bioluminescence-based chemical screen identifies a bactericidal naphthalene scaffold targeting MmpL3 in Mycobacterium abscessus