Mycobacteria-host interactions in human bronchiolar airway organoids
Nino Iakobachvili, Stephen Adonai Leon‐Icaza, Kèvin Knoops, Norman Sachs, Serge Mazères, Roxane Siméone, António Peixoto, Célia Bernard, M. Murris‐Espin, Julien Mazières, Kaymeuang Cam, Christian Chalut, Christophe Guilhot, Carmen López‐Iglesias, Raimond B. G. Ravelli, , Peter J. Peters
This study uses human airway organoids to model tuberculosis infection, showing mycobacteria infect epithelial cells with low efficiency and the organoid microenvironment controls but does not eliminate the pathogen.
Molecular Microbiology · Oct 5, 2021Peer-reviewedSystems Biology