Author

Fabien Segui

Scientific Centre of Monaco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jérôme DurivaultiD· 2 shared Marina PagnuzziiD· 2 shared Milica VučetićiD· 2 shared Valérie VialiD· 2 shared Vincent PiccoiD· 2 shared Annael BerniniiD· 1 shared Delphine DebayleiD· 1 shared Doria FilipponiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Jérôme DurivaultORCID

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2 papers

Recent·Most cited

MMRi62 induces iron depletion-driven apoptosis through a ferritin-independent mechanism

Fabien Segui, Marina Pagnuzzi, Julie Antiq, Jérôme Durivault, Valérie Vial, Nicolas Bogliotti, Isabelle Leray, Milica Vučetić, Vincent Picco

This study shows MMRi62 induces iron depletion-driven apoptosis in medulloblastoma cells without requiring ferritin degradation or ferroptosis.

bioRxiv · Sep 23, 2026 · PreprintCancer Biology

Deletion of Ferritin Heavy Chain Limits Tumor Growth and Promotes Iron-Dependent Stress in Medulloblastoma

Fabien Segui, Jérôme Durivault, Marina Pagnuzzi, Valérie Vial, Annael Bernini, Doria Filipponi, 武士原山, Pauline Perne, Delphine Debayle, Kévin Müller, Eddy Pasquier, Marion Le Grand, Scott K. Parks, Yann Cormerais, Jacques Pouysségur, , Vincent Picco

This study shows that deleting ferritin heavy chain in medulloblastoma cells limits tumor growth by promoting iron-dependent stress and sensitizing cells to iron toxicity.

bioRxiv · Jul 25, 2026 · PreprintCancer Biology