Zhe Zhang

The paper investigates how different LTBP isoforms regulate TGF-β spatial localization and activation through structural and functional analyses.

The paper introduces CombiDOCK and MINT-Dock to efficiently screen large molecule libraries for ligand discovery, achieving high hit rates and computational efficiency.

This study identifies PKM as a metabolic activator of SARM1 in diabetic neuropathy, showing that inhibiting their interaction reduces axonal degeneration.