All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity
Daniel Severín, Su Z. Hong, Seung‐Eon Roh, Shiyong Huang, Jiechao Zhou, Michelle Bridi, Ingie Hong, Sachiko Murase, Sarah Robertson, Rebecca P. Haberman, Richard L. Huganir, Michela Gallagher, Elizabeth M. Quinlan, Paul F. Worley, Alfredo Kirkwood
The paper shows that monocular deprivation in mouse visual cortex causes an all-or-none elimination of pyramidal cell connections to parvalbumin-positive interneurons, which is necessary for ocular dominance plasticity.
Proceedings of the National Academy of Sciences · Sep 10, 2021Peer-reviewedNeuroscience