Michela Gallagher

Parallel circadian-like oscillations in LTP and excitation inhibition balance in mouse CA1 reverse direction after puberty

The paper shows that LTP and E/I ratio oscillate with the light-dark cycle in mouse CA1, reversing direction after puberty.

Altered NPTX2 dynamics associated with impaired cognitive aging

The paper investigates NPTX2 dynamics in aging rats to understand its role in cognitive aging and neurodegeneration, finding that successful cognitive aging is linked to increased NPTX2 levels and adaptive responses to memory tasks.

Loss of functional heterogeneity along the CA3 transverse axis in aging

This study examines how aging affects functional heterogeneity along the CA3 transverse axis in rats, showing reduced pattern separation in aged memory-impaired rats.

The lateral habenula mediates the association of a conditioned stimulus with the absence of an appetitive unconditioned stimulus

This study investigates how lateral habenula activity influences conditioned inhibition by manipulating its function in vivo and measuring changes in conditioned responses.

All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity

The paper shows that monocular deprivation in mouse visual cortex causes an all-or-none elimination of pyramidal cell connections to parvalbumin-positive interneurons, which is necessary for ocular dominance plasticity.

An optimized tissue clearing protocol for rat brain labeling, imaging, and high throughput analysis

The paper introduces an optimized tissue clearing protocol for rat brains and develops an open-source platform for high-throughput analysis.

Heterogeneity of age-related neural hyperactivity along the CA3 transverse axis

This study examines age-related changes in neural firing rates along the CA3 transverse axis in rats, finding a reversed gradient in hyperactivity compared to young rats.

Age-related Changes in Memory for Object and Position-In-Context

This study examines age-related differences in memory for object and position-in-context, finding reduced performance in recognizing object position changes in older adults compared to younger adults.

AFTERHYPERPOLARIZATION AMPLITUDE IN CA1 PYRAMIDAL CELLS OF AGED LONG-EVANS RATS CHARACTERIZED FOR INDIVIDUAL DIFFERENCES

The paper examines afterhyperpolarization amplitude in aged Long-Evans rats, finding a reduction in cognitively impaired individuals compared to Fisher 344 rats.

Reduced Cognitive Performance in Aged Rats Correlates with Increased Excitation/Inhibition Ratio in the Dentate Gyrus in Response to Lateral Entorhinal Input

This study shows that aging-related cognitive decline in rats is linked to reduced inhibition in the dentate gyrus in response to lateral entorhinal input.