Author

Maya Bose

University of MichiganORCID 0000-0002-4944-6033Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Arushi VarshneyiD· 4 shared Stephen C.J. ParkeriD· 4 shared Adelaide TovariD· 2 shared Barbara Nicklas· 2 shared Eric B. FaumaniD· 2 shared Evanthia E. PashosiD· 2 shared Federico Damilano· 2 shared Jacob Otto KitzmaniD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersGenomics

Arushi VarshneyORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Single-nucleus multi-omics reveals reversible molecular signatures in skeletal muscle of patients with heart failure with preserved ejection fraction

Maya Bose, Arushi Varshney, Nicholas J. Carruthers, Peter Orchard, Mary E. Piper, Evanthia E. Pashos, Vladislav Dolgachev, Nandini Manickam, Erika Curka, Pierre M. Jean Beltran, Dalane W. Kitzman, Eric B. Fauman, Federico Damilano, Rachel J. Roth Flach, Barbara Nicklas, , Stephen C.J. Parker

The paper uses single-nucleus multi-omics to study skeletal muscle changes in HFpEF patients and shows some molecular changes are reversible with lifestyle interventions.

bioRxiv · Oct 9, 2026 · PreprintGenomics

Genetic demultiplexing and transcript start site identification from nanopore sequencing of 10x Genomics multiome libraries

Joseph Mears, Peter Orchard, Arushi Varshney, Maya Bose, Catherine C. Robertson, Mary E. Piper, Evanthia E. Pashos, Vladislav A. Dolgachev, Nandini Manickam, Pierre Jean, Dalane W Kitzman, Eric B. Fauman, Federico Damilano, Rachel J. Roth Flach, Barbara Nicklas, Stephen C.J. Parker

This study demonstrates nanopore sequencing of 10x Genomics multiome libraries to capture full-length transcripts and identify TSS, showing concordance with short-read methods despite higher error rates.

bioRxiv · Apr 8, 2026 · PreprintBioinformatics

Using a modular massively parallel reporter assay to discover context-dependent regulatory activity in type 2 diabetes-linked noncoding regions

Adelaide Tovar, Yasuhiro Kyono, Kirsten Nishino, Maya Bose, Arushi Varshney, Stephen C.J. Parker, Jacob Otto Kitzman

The paper uses MPRAs to assess context-dependent regulatory activity in type 2 diabetes-linked noncoding regions across different promoters and cell types.

Human Genetics and Genomics Advances · Apr 7, 2026Peer-reviewedGenomics

Massively parallel reporter assay reveals promoter-, position-, and strand-specific effects in transcription start sites

Maya Bose, Adelaide Tovar, Yasuhiro Kyono, Arushi Varshney, Jacob Otto Kitzman, Stephen C.J. Parker

The paper uses MPRA to assess context-dependent activity of transcription start sites, finding that promoter, position, and strand effects influence regulatory element function.

bioRxiv · Oct 13, 2025 · PreprintGenomics