Author

Pierre Jean

Pfizer (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:large language model· 1 Assay:long-read sequencing· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Evanthia E. PashosiD· 2 shared Mary E. PiperiD· 2 shared Arushi VarshneyiD· 1 shared Barbara Nicklas· 1 shared Catherine C. RobertsoniD· 1 shared Dalane W Kitzman· 1 shared Daniel WongiD· 1 shared Djork-Arné ClevertiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Evanthia E. PashosORCID

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Author profile →

2 papers

Recent·Most cited

Genetic demultiplexing and transcript start site identification from nanopore sequencing of 10x Genomics multiome libraries

Joseph Mears, Peter Orchard, Arushi Varshney, Maya Bose, Catherine C. Robertson, Mary E. Piper, Evanthia E. Pashos, Vladislav A. Dolgachev, Nandini Manickam, Pierre Jean, Dalane W Kitzman, Eric B. Fauman, Federico Damilano, Rachel J. Roth Flach, Barbara Nicklas, Stephen C.J. Parker

This study demonstrates nanopore sequencing of 10x Genomics multiome libraries to capture full-length transcripts and identify TSS, showing concordance with short-read methods despite higher error rates.

bioRxiv · Apr 8, 2026 · PreprintBioinformatics

Phenotypic reversion and target prioritization for cellular inflammation via representation learning with foundation models

Daniel Wong, Mary E. Piper, Jiao Qiao, Max Russo, Pierre Jean, Djork-Arné Clevert, Jason D. Arroyo, Evanthia E. Pashos

The paper uses single-cell foundation models to identify genetic targets that reverse inflammation in endothelial cells by analyzing Perturb-seq data with and without proinflammatory stimulation.

bioRxiv · Mar 6, 2026 · PreprintBioinformatics