Author

Astrid Zedlitz Johansen

Herlev HospitalORCID 0000-0002-4948-6799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Daniel Hargbøll MadseniD· 3 shared Hannes LinderiD· 3 shared Kevin James BakeriD· 3 shared Klaire Yixin FjæstadiD· 3 shared Lars GrøntvediD· 3 shared Lars Henning EngelholmiD· 2 shared Mads Hald AnderseniD· 2 shared Majken Storm SiersbækiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

Daniel Hargbøll MadsenORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dual targeting of CCR2+ monocytes and neutrophils enhances anti-tumor immunity

Klaire Yixin Fjæstad, Astrid Zedlitz Johansen, Hannes Linder, Marco Carretta, Majken Storm Siersbæk, Kevin James Baker, Marie‐Louise Thorseth, Mie Linder Hübbe, Mads Hald Andersen, Lars Grøntved, Daniel Hargbøll Madsen

This study shows that targeting both CCR2+ monocytes and neutrophils improves anti-tumor immunity by reducing tumor growth and enhancing CD8+ T cell infiltration.

bioRxiv · May 15, 2026 · PreprintCancer Biology

Acquired resistance to immune checkpoint inhibitors is associated with hypoxia and ECM remodeling in colorectal cancer

Astrid Zedlitz Johansen, Hannes Linder, Cecilie Oelvang Madsen, Kevin James Baker, Klaire Yixin Fjæstad, Shawez Khan, Nadia Kolvig Czajkowski, Christian Thygesen, Majken Storm Siersbæk, Frederik Otzen Bagger, Marco Donia, Lars Henning Engelholm, Lars Grøntved, Daniel Hargbøll Madsen

bioRxiv · Apr 29, 2026 · PreprintCancer Biology

Collagen type I promotes pancreatic tumor growth and limits immune cell infiltration

Marie‐Louise Thorseth, Astrid Zedlitz Johansen, Kevin James Baker, Marco Carretta, Anne Mette Askehøj Rømer, C. Jensen, Henrik J. Jürgensen, Hannes Linder, Nadia Kolvig Czajkowski, Dorota Ewa Kuczek, Klaire Yixin Fjæstad, Lars Henning Engelholm, Nicholas Willumsen, Kevin Kim, Mads Hald Andersen, , Daniel Hargbøll Madsen

This study shows that collagen type I promotes pancreatic tumor growth and limits immune cell infiltration in mice, supported by human dataset analysis.

bioRxiv · Jan 10, 2026 · PreprintCancer Biology

Functional Role of Small Extrachromosomal Circular DNA in Colorectal Cancer

Judith Mary Hariprakash, Egija Zole, Weijia Feng, Dan Hao, Lasse Bøllehuus Hansen, Nirmalya Bandyopadhyay, Marghoob Mohiyuddin, Sihan Wu, Astrid Zedlitz Johansen, Julia Sidenius Johansen, Birgitte Regenberg

This study investigates the role of small extrachromosomal circular DNA (eccDNA) in colorectal cancer, finding that it contributes to gene expression, immune cell recruitment, and poor patient outcomes.

bioRxiv · Aug 1, 2025 · PreprintCancer Biology