Emilie Lavallée

The paper identifies mitochondrial protein signatures that determine sensitivity to PLK1 inhibitors in melanoma, showing that mitochondrial DNA depletion and ABCD1 silencing enhance sensitivity and reduce pro-inflammatory responses.

This paper identifies ATP5I as a target of metformin, showing its role in mediating metabolic and antiproliferative effects through mitochondrial dysfunction and altered ATP synthase oligomerization.