Mathieu Mancini

This study shows that immune receptors on hematopoietic progenitor cells are upregulated in a mouse model of rheumatoid arthritis and that stimulating these receptors alters cell expansion and differentiation.

This study identifies IRF1 as a pioneer factor that remodels chromatin and drives metabolic reprogramming in inflammatory macrophages through enhancer activation and transcriptional control.

This study shows that trained immunity affects dendritic cell differentiation and function in rheumatoid arthritis, altering their gene expression and immune responses.