Author

Warren D. Kruger

Fox Chase Cancer CenterORCID 0000-0002-4990-3695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Aalim M. WeljieiD· 1 shared Aziz SancariD· 1 shared Baiqing TangiD· 1 shared Christopher P. SelbyiD· 1 shared Dania M. MalikiD· 1 shared Daniel KrzizikeiD· 1 shared Eylem Kulkoyluoglu‐CotuliD· 1 shared Hande AsimgiliD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Aalim M. WeljieORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Febuxostat enhances the anti-tumor efficacy of 2-fluoroadenine and 5-methylthioadenosine in MTAP-deleted cancer

Baiqing Tang, Hyung‐Ok Lee, Daniel Krzizike, Kathy Qi Cai, Sapna Gupta, Warren D. Kruger

The paper shows that adding febuxostat to 2FA and MTA increases their anti-tumor effect in MTAP-deleted cancer by reducing XO activity and increasing 2FAMP levels.

Cancer Research Communications · Jul 31, 2026Peer-reviewedCancer Biology

CRY1-CBS binding regulates circadian clock function and metabolism

Sibel Cal‐Kayitmazbatir, Eylem Kulkoyluoglu‐Cotul, Jacqueline Growe, Christopher P. Selby, Seth D. Rhoades, Dania M. Malik, Haşimcan Öner, Hande Asimgil, Lauren J. Francey, Aziz Sancar, Warren D. Kruger, John B. Hogenesch, Aalim M. Weljie, Ron C. Anafi, İbrahim Halil Kavaklı

This study identifies CBS-CRY1 binding as a regulatory mechanism linking circadian rhythms and metabolism, showing that CBS modulates CRY1 activity and vice versa.

FEBS Journal · May 8, 2020Peer-reviewedMolecular Biology