Peter Loskill

Functional primary human 3D skeletal muscle models enable exercise and metabolic research

The paper develops primary human skeletal muscle organoids that mimic metabolic and exercise responses, showing alignment with in vivo responses and detecting drug effects.

Electrophysiological profiling of hiPSC-derived neurospheres using a novel NeuroMPS with integrated electrodes

This paper develops a novel NeuroMPS platform to monitor neuronal network dynamics in 3D human iPSC-derived neurospheres with high electrophysiological resolution and multimodal analysis.

Ovarian cancer-on-chip for patient-specific profiling of treatment responses to sequential chemotherapy and PD-L1 blockade

This paper develops an OvCa-on-chip platform to profile patient-specific treatment responses to chemotherapy and PD-L1 blockade.

A scalable mesh microelectrode array platform for longitudinal electrophysiology in neural spheroids

This paper introduces a mesh microelectrode array platform for longitudinal electrophysiology in neural spheroids, enabling recordings and pharmacological modulation of electrical activity.

Lymphoid-tissue-on-chip recapitulates human antibody responses in vitro

This study develops a lymphoid-tissue-on-chip model that recapitulates human antibody responses to influenza vaccines in vitro.

Cancer-mediated Axonal Guidance of Sensory Neurons in a Microelectrode-based Innervation MPS

This paper introduces a novel microelectrode-based 3D coculture system (INV-MPS) to study cancer-mediated axonal guidance and nociception in vitro, showing cancer spheroids can direct axonal growth and modulate neuronal excitability.