Eric R. Lucas

This study identifies multiple insecticide resistance mechanisms in Angolan Aedes aegypti using transcriptomic analysis, revealing shared and novel resistance genes compared to other regions.

This study uses whole-genome sequencing to analyze genomic connectivity and adaptive gene flow of insecticide resistance alleles in Anopheles arabiensis across East Africa, revealing transboundary spread despite geographic barriers.

This study analyzes whole genomes of 1094 Anopheles darlingi mosquitoes from six South American countries, revealing geographic structure, genetic diversity, and selection signals on cytochrome P450 genes.

This study uses genomic data to analyze evolutionary dynamics of Anopheles gambiae under different insecticidal tools, revealing distinct resistance mechanisms and allele frequency shifts.

This study identifies loci and mutations associated with pyrethroid resistance in Anopheles gambiae species complex using multi-omics data and finds potential diagnostic markers and introgression between species.

The paper analyzes genomic diversity in Anopheles funestus across Africa, identifying genetic variation, adaptation signals, and conservation of a gene drive target.

This study compares static and dynamic flow culture conditions in human airway models to show that dynamic flow improves tissue architecture, infection dynamics, and predictive power for SARS-CoV-2 infection.

This paper uses genomic surveillance in a cluster randomized trial to detect insecticide resistance variants in Ugandan Anopheles funestus and An. gambiae s.l., showing differential population responses to pyrethroid and PBO interventions.

This study traces the origin and spread of Anopheles stephensi in Africa using genomic data and identifies insecticide resistance genes from Asia.

This paper develops a targeted genomic surveillance approach for insecticide resistance in malaria vectors, identifying resistance variants and demonstrating predictive modeling with high accuracy.

The paper investigates insecticide resistance and population structure in Anopheles gambiae from southern DRC, finding high resistance and genetic differentiation between populations.

The paper identifies cis-regulated genes and cis-regulatory modules in Anopheles gambiae associated with insecticide resistance using allele-specific expression and machine learning.

This study sequenced 1,206 Aedes aegypti genomes to trace the origin and global spread of the species, revealing its evolution from a forest-dwelling to an urban, human-biting form and its impact on dengue risk.

This study identifies a duplicated esterase locus associated with pirimiphos-methyl resistance in Anopheles gambiae through population genomic analysis.

This study identifies copy number variants (CNVs) as key drivers of insecticide resistance in Anopheles arabiensis, revealing new gene clusters and resistance mechanisms to deltamethrin and pirimiphos-methyl.

This study applies a spatially explicit sampling framework in coastal Kenya to identify high mosquito abundance areas and improve vector control strategies.

This study identifies novel genetic loci associated with resistance to pyrethroid and organophosphate insecticides in Anopheles gambiae s.l. through genome-wide association analyses.

This study integrates whole genome sequencing and transcriptomics to identify multiple factors contributing to insecticide resistance in Anopheles coluzzii.

The paper identifies a resistance mechanism to pirimiphos-methyl in Anopheles mosquitoes through duplication and introgression of the Ace1 locus, showing its spread in West Africa.

The paper analyzes genome variation in 1,142 Anopheles mosquitoes to study population structure and insecticide resistance.