Author

Brett Lomenick

California Institute of TechnologyORCID 0000-0002-5023-9998Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Organism:human· 1

Frequent Co-Authors

Alexei A. AraviniD· 1 shared Annie MoradianiD· 1 shared Bryan Vander Lugt· 1 shared David J. ShermaniD· 1 shared Hannah Holmes· 1 shared James A. JohnstoniD· 1 shared James Russell Lipford· 1 shared Jennifer L. MamroshiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Alexei A. AravinORCID

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2 papers

Recent·Most cited

Pervasive SUMOylation of heterochromatin and piRNA pathway proteins

Maria Ninova, Hannah Holmes, Brett Lomenick, Katalin Fejes Tóth, Alexei A. Aravin

The paper identifies SUMOylation targets in Drosophila ovary, revealing its role in heterochromatin regulation and piRNA pathway function.

Cell Genomics · May 18, 2023Peer-reviewedMolecular Biology

A Systematic Interrogation of MHC Class I Peptide Presentation Identifies Constitutive and Compensatory Protein Degradation Pathways

Jennifer L. Mamrosh, David J. Sherman, Joseph R. Cohen, James A. Johnston, Marisa K. Joubert, Jing Li, James Russell Lipford, Brett Lomenick, Annie Moradian, Siddharth Prabhu, Michael J. Sweredoski, Bryan Vander Lugt, Rati Verma, Raymond J. Deshaies

The paper quantifies MHC Class I peptide origins under UPS perturbation, revealing 30% of peptides are UPS-independent and 10% proteasome-independent, with implications for immune activation.

bioRxiv · Oct 7, 2021 · PreprintMolecular Biology