Benjamin Ehret

Modular engineered colorectal tumor microenvironments for immuno-oncology research and drug development

This paper introduces SHOCOs, a modular system using patient-derived colorectal tumor organoids and fibroblasts to model tumor microenvironments, showing improved immune response and stromal effects on therapy.

Inhibition tunes prefrontal circuit dynamics to promote sociosexual behavior in female mice

This study shows that inhibiting oxytocin receptor neurons in the medial prefrontal cortex promotes sociosexual behavior in female mice by regulating pyramidal neuron activity during decision-making.

Population-level neural correlates of flexible avoidance learning in medial prefrontal cortex

This study uses calcium imaging in mice to identify population-level neural activity in the medial prefrontal cortex during avoidance learning, showing that avoidance-related activity predicts behavior and distinguishes between different learned actions.

How synaptic strength, short-term plasticity, and input synchrony contribute to neuronal spike output

The paper investigates how synaptic strength, short-term plasticity, and input synchrony influence neuronal spiking output in mouse neocortex using experimental and computational methods.

Fast retrograde access to projection neuron circuits underlying vocal learning in songbirds

The paper introduces a viral tool for fast retrograde labeling of projection neurons in songbirds and mice, enabling detailed analysis of vocal learning circuits.