Author

Andrew Sharkey

University of CambridgeORCID 0000-0002-5072-7748Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Anna ArutyunyaniD· 1 shared Ashley MoffettiD· 1 shared Ayano Nakazawa· 1 shared Carla R. NowosadiD· 1 shared Carmen Sancho‐SerraiD· 1 shared Delphine DepierreuxiD· 1 shared Elisa MagistratiiD· 1 shared Francesco ColucciiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperDevelopmental Biology

Anna ArutyunyanORCID

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2 papers

Recent·Most cited

Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development

Natalie Samper, Lilja Harðardóttir, Delphine Depierreux, Soomin C. Song, Ayano Nakazawa, Ivan Gando, Tomoe Y. Nakamura, Andrew Sharkey, Carla R. Nowosad, Stefan Feske, Francesco Colucci, William A. Coetzee

This study identifies Kir6.1 as a key regulator of natural killer cell development in mice, showing its expression in mature NK cells and its role in NK-cell differentiation.

Frontiers in Immunology · Dec 2, 2024Peer-reviewedImmunology

Successful placentation in human pregnancy is regulated by reciprocal interactions between maternal uterine NK cells and fetal placental trophoblast

Qian Li, Andrew Sharkey, Megan A. Sheridan, Elisa Magistrati, Anna Arutyunyan, Oisín Huhn, Carmen Sancho‐Serra, Holly E. Anderson, Naomi N. McGovern, Laura Esposito, Ridma C. Fernando, Lucy Gardner, Roser Vento‐Tormo, Margherita Yayoi Turco, Ashley Moffett

The paper identifies a uNK-derived cytokine signal that promotes trophoblast differentiation and influences placental function and pregnancy outcomes.

Cell stem cell · Jan 17, 2024Peer-reviewedDevelopmental Biology