Shanhui Liao

Molecular basis for PICS-mediated piRNA biogenesis and cell division

This study maps the interaction network of the C. elegans PICS complex and reveals structural and functional mechanisms underlying piRNA biogenesis and cell division.

Molecular basis for cysteine oxidation by Plant Cysteine Oxidases from Arabidopsis thaliana

The paper presents structures of Arabidopsis thaliana PCOs and identifies key residues for N-Cys oxidation, revealing substrate recognition and catalytic mechanisms.

Differential phase partition of a PICS complex is required for piRNA processing and chromosome segregation in C. elegans

The paper identifies a PICS complex involved in piRNA processing and chromosome segregation in C. elegans, with distinct localization and function in different cellular contexts.