Author

Chenming Zeng

University of Science and Technology of China

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 2 Assay:DNA methylation· 1 Approach:statistical model· 1

Frequent Co-Authors

Shouhong GuangiD· 4 shared Xuezhu FengiD· 3 shared Chao XuiD· 2 shared Chenchun WengiD· 2 shared Eric Alexander MiskaiD· 2 shared Meng‐Qiu DongiD· 2 shared Shanhui LiaoiD· 2 shared Wen-Jun LiiD· 2 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersMolecular Biology

Shouhong GuangORCID

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4 papers

Recent·Most cited

A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory

Chenming Zeng, Giulia Furlan, Miguel Vasconcelos Almeida, Juan C. Rueda-Silva, Jonathan L. Price, Helena Santos-Rosa, Jingxiu Xu, Yan Kuang, Enric Cata Socias, Jonas Mars, Pedro Rebelo‐Guiomar, M. R. Huang, Shouhong Guang, Falk Butter, Eric Alexander Miska

This study identifies SET-24, a catalytically inactive SET domain protein in C. elegans, as essential for maintaining transgenerational epigenetic memory through its interaction with HCF-1 and regulation of H3K4me3 levels.

Nature Communications · Jan 9, 2026Peer-reviewedMolecular Biology

Molecular basis for PICS-mediated piRNA biogenesis and cell division

Xiaoyang Wang, Chenming Zeng, Shanhui Liao, Zhongliang Zhu, Jiahai Zhang, Xiaoming Tu, Xuebiao Yao, Xuezhu Feng, Shouhong Guang, Chao Xu

This study maps the interaction network of the C. elegans PICS complex and reveals structural and functional mechanisms underlying piRNA biogenesis and cell division.

Nature Communications · Sep 22, 2021Peer-reviewedMolecular Biology

Differential phase partition of a PICS complex is required for piRNA processing and chromosome segregation in C. elegans

Chenming Zeng, Chenchun Weng, Xiaoyang Wang, Yonghong Yan, Wen-Jun Li, Demin Xu, Minjie Hong, Shanhui Liao, Xuezhu Feng, Meng‐Qiu Dong, Chao Xu, Shouhong Guang

The paper identifies a PICS complex involved in piRNA processing and chromosome segregation in C. elegans, with distinct localization and function in different cellular contexts.

bioRxiv · Nov 6, 2018 · PreprintGenetics

The USTC complex co-opts an ancient machinery to drive piRNA transcription in C. elegans

Chenchun Weng, Asia Kosalka, Ahmet Can Berkyurek, Przemysław Stempor, Xuezhu Feng, Hui Mao, Chenming Zeng, Wen-Jun Li, Yonghong Yan, Meng‐Qiu Dong, Cecilia Zuliani, O. Barábas, Julie Ahringer, Shouhong Guang, Eric Alexander Miska

The paper identifies the USTC complex as essential for piRNA transcription in C. elegans, revealing its role in genome defense through specific binding to piRNA clusters.

bioRxiv · Jul 30, 2018Developmental Biology